The PeRSEVERE project is about what should happen when research participants stop, reduce or change their involvement in clinical trials and other research studies.

The PeRSEVERE principles were developed with input from patients and research professionals from various disciplines and backgrounds.

On this site, you will find details of the PeRSEVERE principles, resources and guidance about how to put them into practice, and information about what the principles might mean for your own involvement in research.

The resources on this site are intended for research professionals, and patients or members of the public involved in research.

Our principles guide everyone involved in managing or preparing for participation changes to do it in ways that do the best by research participants and the studies they take part in.